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Moonshine

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Potential cancer applications

Cancer cells generally use glycolysis rather than oxidation for energy (the Warburg effect), as a result of hypoxia in tumors and damaged mitochondria.[8] The body often kills damaged cells by apoptosis, a mechanism of self-destruction that involves mitochondria, but this mechanism fails in cancer cells.

 

A study published in January 2007 by researchers at the University of Alberta,[9] testing DCA on in vitro cancer cell lines and a rat model, found that DCA restored mitochondrial function, thus restoring apoptosis, killing cancer cells in vitro, and shrinking the tumors in the rats.[10]

 

These results received extensive media attention, beginning with an article in New Scientist titled "Cheap, Safe Drug Kills Most Cancers".[11] Subsequently, the American Cancer Society and other medical organizations have received a large volume of public interest and questions regarding DCA.[12] Reports have since pointed out that although the study results are promising, no clinical trials in humans with cancer have yet been conducted, emphasizing the need for caution in interpreting the preliminary results.[12][13] No data from clinical trials are available yet.

 

The New Scientist later editorialized, "The drug may yet live up to its promise as an anti-cancer agent - clinical trials are expected to start soon. It may even spawn an entirely new class of anti-cancer drugs. For now, however, it remains experimental, never yet properly tested in a person with cancer. People who self-administer the drug are taking a very long shot and, unlikely as it may sound, could even make their health worse."

 

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